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Oral One PAP

The Oral One PAP ® is a molecular test, which provides a comprehensive screening of a range of infectious diseases particularly those extra genital oral infections that are transmitted sexually. In addition, the Oral One PAP® is designed to screen for oropharyngeal carcinoma and to diagnose syndromic acute pharyngitis. 

Oral One PAP  Panel Menu

Performance:100% sensitivity and 99.8% specificity 
Sample Type: Oropharyngeal Rinse

Methodology: Real-Time PCR

STI Molecular Assay Panel

Acute Pharyngitis Assay Molecular Panel

Chlamydia trachomatis

Escherichia coli 

Enterococcus faecalis 

Mycoplasma genitalium 

Neisseria gonorrhoeae

Treponema pallidum

Shigella flexneri

Hepatitis B Virus    

Hepatitis C Virus     


Herpes Simplex Virus 1

Herpes Simplex Virus 2

Streptococcus dysgalactiae

Streptococcus pyrogenes

Epstein Barr Virus 

Trichomonas vaginalis  

Giardia lamblia

Entamoeba histolytica

Candida albicans

Candida glabrata

Candida parapsilosis

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Oropharyngeal Cancer Assay Panel 

*  If HPV infection present:
Reflex to High risk E6/E7 mRNA

Oral Cytology (Optional)

High-Risk human papillomavirus (HPV) DNA

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An Alarming Epidemic

There has been an exponential increase in sexually transmitted infections in the U.S, causing the CDC to declare an epidemic. Current evidence demonstrates that extra genital STI's of the oropharyngeal cavity are often asymptomatic and may not be associated with concurrent positive urogenital infections. 

Facts about STDs and Oral Sex


It is possible to get certain STDs on the genitals and genital areas after receiving oral sex from a partner with a mouth or throat infection.


Several STDs (i.e., syphilis, gonorrhea, and intestinal infections) that are transmitted by oral sex can spread in the body.


Oral sex involving the anus (or anilingus) can transmit hepatitis A and. It also can transmit intestinal parasites like Giardia 

and bacteria like E.coli and Shigella.


If you have an STD, you might not know it because many STDs are symptomless. It is possible to spread STDs even when you don’t have any signs or symptoms.



It is possible to get some STDs in the mouth or throat after giving oral sex to a partner who has a genital or anal/rectal STD.

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Ultra Solutions

Molecular Reporting 

For negative results PCG Molecular will send your patients an email on your behalf within 24 hours if patient results are negative for “watch” or high risk results. Being placed on a watch for presence of HPV 16-18 is no reason for patients to panic. It doesn’t mean they have oral cancer or that they will ever get it. All it means is that we need to watch their cases more closely. We will send you a report and give you a sample letter to send to your patients that communicates the results and what next steps to follow. for positive results. You will receive a detailed report for those patients that test positive for oncogenic viral related sexually transmitted infections. These patients may require additional tests after treatment, along with a personal call. We can advise you of next steps and referrals if you need them. 

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