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Anal One PAP  

The Anal One PAP screens for presence of Human Papilloma Virus (HPV) DNA  as well as precancerous cells  to determine whether a patient  is at high-risk for developing precancerous or cancerous conditions. – in addition Anal One PAP is design to test for a host of other infectious anal conditions.

Anal One PAP Panel Menu

Performance: 100% sensitivity and 99.8% specificity 
Sample Type: Anal-Rectal

Methodology: Real-Time PCR

STI Molecular Assay Panel


Human papillomavirus genotypes

Chlamydia trachomatis 

Trichomonas vaginalis

Neisseria gonorrhoeae 

Mycoplasma genitalium 

Mycoplasma hominis

Ureaplasma urealyticum

Ureaplasma parvum 

Herpes simplex virus Type 1

Herpes simplex virus Type 2

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HPV is the cause of most cases of anal cancer


The same sexually-transmitted disease, HPV, that causes so many abnormal pap smears in women every year is also the cause of a majority of cases of anal cancer. Annual anal pap smears can change the course of this disease, much as regular cervical cancer pap testing has done. Anal cancer is on the rise. Cases have tripled since 1970, and late-stage cases result in a 20% survival rate beyond five years. Although there is only a 1 in 500 chance of developing the disease, it is preventable and often curable if caught early.

Why is Anal One PAP better? 


Typically doctors screen for anal cancer through a test known as the DRE (Digital Rectal Exam). It’s invasive, may not catch things higher in the anal cavity and there is room for human error. In addition, the Anal One PAP uses a brush device to collect cells for cytology and anal molecular infectious pathogens. The anal sample is then sent to PCG Molecular diagnostic laboratory for testing and interpretation

Ultra Solutions

Molecular Reporting 

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For negative results PCG Molecular will send your patients an email on your behalf within 24 hours if patient results are negative for “watch” or high risk results. Being placed on a watch is no reason for patients to panic. It doesn’t mean they have anal cancer or that they will ever get it. All it means is that we need to watch their cases more closely. We will send you a report and give you a sample letter to send to your patients that communicates the results and what next steps to follow. for positive results. You will receive a detailed report for those patients that test positive for any viral related sexually transmitted infections. These patients may require additional tests after treatment, along with a personal call. We can advise you of next steps and referrals if you need them. 

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